Liu Y, Wang L, Fatahi R, Kronenberg M, Kalajzic I, Rowe D, Li Y, Maye P (2010) Isolation of murine bone marrow derived mesenchymal stem cells using Twist2 Cre transgenic mice. Kronenberg HM (2004) Twist genes regulate Runx2 and bone formation. Krampera M, Marconi S, Pasini A, Galie M, Rigotti G, Mosna F, Tinelli M et al (2007) Induction of neural-like differentiation in human mesenchymal stem cells derived from bone marrow, fat, spleen and thymus. Keilhoff G, Goihl A, Langnase K, Fansa H, Wolf G (2006) Transdifferentiation of mesenchymal stem cells into Schwann cell-like myelinating cells. Kalajzic Z, Li H, Wang LP, Jiang X, Lamothe K, Adams DJ, Aguila HL, Rowe DW, Kalajzic I (2008) Use of an alpha-smooth muscle actin GFP reporter to identify an osteoprogenitor population. Jiang Y, Jahagirdar BN, Reinhardt RL, Schwartz RE, Keene CD, Ortiz-Gonzalez XR, Reyes M et al (2002) Pluripotency of mesenchymal stem cells derived from adult marrow. Gronthos S, Zannettino AC, Hay SJ, Shi S, Graves SE, Kortesidis A, Simmons PJ (2003) Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow. Gronthos S, Graves SE, Ohta S, Simmons PJ (1994) The STRO-1+ fraction of adult human bone marrow contains the osteogenic precursors. J Embryol Exp Morphol 16(3):381–390įriedenstein AJ, Chailakhjan RK, Lalykina KS (1970) The development of fibroblast colonies in monolayer cultures of guinea-pig bone marrow and spleen cells. Prog Clin Biol Res 148:13–33įriedenstein AJ, Shapiro Piatetzky II, Petrakova KV (1966) Osteogenesis in transplants of bone marrow cells. Cells Tissues Organs 170(2–3):73–82ĭexter TM, Simmons P, Purnell RA, Spooncer E, Schofield R (1984) The regulation of hemopoietic cell development by the stromal cell environment and diffusible regulatory molecules. Bone 39(3):513–522ĭennis JE, Carbillet JP, Caplan AI, Charbord P (2002) The STRO-1+ marrow cell population is multipotential. Mol Biotechnol 20(3):245–256ĭ’Ippolito G, Diabira S, Howard GA, Roos BA, Schiller PC (2006) Low oxygen tension inhibits osteogenic differentiation and enhances stemness of human MIAMI cells. Dev Cell 6(3):423–435Ĭaterson EJ, Nesti LJ, Danielson KG, Tuan RS (2002) Human marrow-derived mesenchymal progenitor cells: isolation, culture expansion, and analysis of differentiation. J Cell Biochem 89(6):1235–1249īialek P, Kern B, Yang X, Schrock M, Sosic D, Hong N, Wu H et al (2004) A twist code determines the onset of osteoblast differentiation. J Cell Physiol 218(2):237–245īaddoo M, Hill K, Wilkinson R, Gaupp D, Hughes C, Kopen GC, Phinney DG (2003) Characterization of mesenchymal stem cells isolated from murine bone marrow by negative selection. This process is experimental and the keywords may be updated as the learning algorithm improves.Īrthur A, Zannettino A, Gronthos S (2009) The therapeutic applications of multipotential mesenchymal/stromal stem cells in skeletal tissue repair. ![]() These keywords were added by machine and not by the authors. Bone Marrow Derive Mesenchymal Stem Cell.We also include detailed information on mouse BMSCs and methods that we have developed over the past few years to isolate, identify, and work with mouse BMSCs. In this chapter, we discuss the current beliefs in the field with regard to the therapeutic benefit of BMSCs and how we define BMSCs. While human BMSC research has direct therapeutic application, we believe murine animal models have an important role to play in understanding mechanisms of BMSC biology that are likely to influence how BMSCs are therapeutically used. The rare presence of BMSCs within the bone marrow has made it a challenge to understand how this adult stem cell population naturally functions in vivo. One of the more highly investigated adult stem cell populations has been the bone marrow derived mesenchymal stem cell (BMSC). There is a general belief that adult stem cells are an essential aspect of maintaining tissue health as we age and undergo wound healing, but the mechanisms by which adult stem cells contribute to these processes are poorly understood.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |